Integral Maps Summary Sheets

These analyses apply different criteria to define spot clusters of co-regulated metagenes: overexpression and underexpression, mutual correlations between the metagenes, k-means clustering and cluster detection in the distance map. Gene set enrichment analysis provides the leading sets of each of the spots considered. Spot-related heatmaps characterize the expression profiles of the selected features in the series of samples. Single spot summary sheets provide detailed information on each of the spots such as the ranked list of samples which overexpress this feature in decreasing order according to the mean t-statistics of the spot and the ranked list of the overrepresented gene sets together with the histogram of the respective p-value distribution.

Summary Sheets Spot's CSV tables
Overexpression (PDF) ABCDEFG
Overexpresion Signatures (CSV)
Group Overexpression (PDF) ABCDE
Underexpression (PDF) abcdef
Correlation Cluster (PDF) ABCDEFGHIJKLMNOPQRSTUVWXYZA1B1C1D1
K-Means Cluster (PDF) ABCDEFGHIJKLMNOPQRST
Distance Map Clusters (PDF) ABCDEF

Spot Module Report Sheets

Reports contain the spot module expression profiles and assignments of the spots to samples and to groups.

Spot Module Network Analysis

Networks of spot association are visualized as graphs. WTO, correlation networks and correlation spanning trees, are given for individual spots and spot patterns.

Chromosomal Enrichment

For each spot, enrichment of chromosomal postitions (chromosome/band) is visualized as overview heatmaps and individual chromosome plots.